Pakistan Journal of Medical Sciences
Pakistan Journal of Medical Sciences
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Latest posts
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Differential treatment response of postoperative delirium in a patient with Parkinson’s disease following hip surgery: A case report and literature review
Parkinson’s disease (PD) is a common neurodegenerative disease clinically characterized by resting tremor, slowness of movement, myotonia, and postural disequilibrium. In this study, we report a patient diagnosed with PD was admitted to The Second Hospital of Qinhuangdao. The…
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Remimazolam-based total intravenous anesthesia for prone cervical spine surgery in a patient with previously undiagnosed dilated cardiomyopathy after aborted anesthetic induction: A case report
Unexpected hemodynamic deterioration during anesthesia induction may show previously undiagnosed cardiac dysfunction. Herein, we report a case of successful remimazolam-based total intravenous anesthesia in a patient with newly diagnosed dilated cardiomyopathy (DCMP) who…
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Concurrent Fabry disease and Hepatitis-B virus-associated IgA nephropathy: A case report with pain as a precursor
We report a 35-year-old man with Fabry disease coexisting with Hepatitis-B virus (HBV)-associated IgA nephropathy who had been treated for “rheumatism” for many years. He presented with severe burning pain in his extremities, microscopic hematuria and nephrotic-range…
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Pulmonary opacity unresponsive to anti-infective therapy: Clinical insights from a case ultimately diagnosed as lung adenocarcinoma
Lung cancer ranks as the second most commonly diagnosed malignancy worldwide and remains the leading cause of cancer-related mortality. This case report is of a 77-year-old male smoker presented with a three-month history of cough and white sputum, unresponsive to multiple…
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How is UK dentistry adapting to the growing demand for NHS dental services?
Going into 2026, dentistry faces significant challenges in meeting the demand for dental appointments, with approximately 13 million people in the UK reporting unmet dental and oral health needs. 1 Access inequalities and affordability issues mean many patients avoid…
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Efficacy of topical bupivacaine in reducing pain after tonsillectomy: A systematic review and meta-analysis of RCTs
Objectives : This review aimed to assess the efficacy of topical bupivacaine in reducing pain in patients undergoing tonsillectomy. Methodology : PubMed, Embase, CENTRAL, Web of Science, and Google Scholar were searched for randomized controlled trials (RCTs). Pain data were…
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Can think-aloud sessions enhance critical thinking in medical students? evidence from third-year MBBS students
Objective: The objective of this study was to evaluate the effect of think-aloud methodology on critical thinking scores among third-year MBBS students. Methodology: A quasi-experimental pre-test and post-test design was conducted at Jinnah Sindh Medical University, Karachi.…
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Experience summary of Modified Devine Procedure for the treatment of concealed penis
Objective: To summarize and analyze the treatment experience for concealed penis by collecting clinical data of patients who underwent the modified Devine procedure at the Second Hospital of Hebei Medical University. Method: A retrospective analysis was conducted on the clinical…
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Video-based assessment of clinical skills in medical education: A mixed-methods study
Objective: Video-based assessment (VBA) is increasingly used in medical education as a method to evaluate clinical skills objectively and flexibly. However, limited research has focused on students’ and faculty members’ perceptions regarding its implementation, feasibility and…
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Diagnostic accuracy of shear wave and strain elastography in differentiating benign and malignant thyroid nodules
Objective: This study assesses diagnostic accuracy of shear wave elastography (SWE) and strain elastography (SE) for thyroid nodule characterization in keeping histopathology as gold standard. Methodology: It was analytical cross-sectional study at Dow Institute of Radiology…
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Effects of syndrome-differentiated nursing combined with emotional regulation on clinical outcomes and quality of life in patients with functional constipation treated with fire needling
Objective: To evaluate the effects of syndrome-differentiated nursing combined with emotional regulation on clinical outcomes and quality of life in patients with functional constipation (FC) undergoing fire needle acupuncture. Methodology: In this prospective study, 96 patients…
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Subjective recovery in severe mental illnesses: Associations with self-stigma and clinical insight
Objective: This study examined how self-stigmatization and insight affect subjective recovery in individuals with severe mental illness. Methodology: This cross-sectional descriptive study included 131 patients with SMI who were admitted to the Psychiatry outpatient clinic of a…
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Inter-Rater and Intra-Rater reliability of rehabilitative ultrasound imaging of core muscle thickness in individuals with Anterior Pelvic Tilt
Background & Objectives: Excessive lordotic curvature of the lumbar spine defines the phenomenon known as anterior pelvic tilt, which causes changes in posture, movement, and core muscle activation. Rehabilitative ultrasound imaging (RUSI) has been proposed as an effective means…
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Diagnostic performance of conventional and contrast-enhanced ultrasound for extrathyroidal extension in papillary thyroid carcinoma
Objective: To evaluate and compare the diagnostic performance of conventional ultrasound (US) and contrast-enhanced ultrasound (CEUS) for extrathyroidal extension (ETE) in papillary thyroid carcinoma (PTC). Methodology: This study retrospectively analyzed imaging data from 150…
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Retrospective discriminative performance of an exploratory modified early obstetric warning score for identifying critical obstetric conditions in pregnant and puerperal women
Objective: To compare the retrospective discriminative performance of the modified early warning score (MEWS), modified early obstetric warning score (MEOWS), and an exploratory modified MEOWS (MMEOWS) for identifying critical obstetric conditions in pregnant and puerperal…
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Maternal serum alpha-fetoprotein, fetal fraction, and prognostic nutritional index in relation to adverse pregnancy outcomes
Objectives: To evaluate the association of maternal serum alpha-fetoprotein (AFP) with adverse pregnancy outcomes and to investigate its relationship with fetal fraction (FF) and the Prognostic Nutritional Index (PNI) as potential indicators of placental function and maternal…
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Managing dentin hypersensitivity: An In-Vitro comparison of commercially available desensitizing agents
Objective: To evaluate the in-vitro dentin tubule-occluding ability of three commercial desensitizing toothpastes and identify the most effective option for managing dentin hypersensitivity. Methodology: This in-vitro comparative study was conducted at the IIDC dental materials…
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Cognitive function in pregnant women with and without gestational or pre-gestational diabetes mellitus
Objective: The current study aimed to assess Cognitive Function in Pregnant Women with and without Gestational or Pre-Gestational Diabetes Mellitus. Methodology: This analytical cross-sectional comparative study was conducted in the outpatient department of Obstetrics and…
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Establishment of a reference interval for cerebrospinal fluid Orexin-A in children and its diagnostic cutoff value for narcolepsy
Objective: To establish a clinical reference interval of cerebrospinal fluid orexin-A (CSF orexin-A) in children, and to evaluate its diagnostic value and optimal cutoff value for childhood narcolepsy. Methodology: This single-center retrospective study enrolled 214 children…