Genetics Digest
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Latest posts
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Genomics investing 101
When a scientist thinks about genomics, some of the first things that come to her mind may be genome sequencing, CRISPR, even direct-to-consumer ancestry DNA tests. But run this same question by a Wall Street analyst and you will find the allure of the field extends far beyond…
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Are governments using DNA data ethically?
DNA data has the potential to transform the way we carry out scientific and medical research. However, scientists and bioethicists worry that the technology is racing ahead of the ethics committees and regulators that seek to control its power. DNA data is generated by taking a…
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Genomic altruism in the era of Big Data and fragile privacy
If money were no issue or if you were invited to have your genome sequenced free of charge and donate your anonymized data for biomedical research, would you do it? Put in a different way: are you a genomic altruist? Earlier this year a special issue of the journal Big Data &…
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CAR-T therapy: fighting fire with a flood
The body’s own immune system has an important role in battling cancer, and it is no surprise that scientists are exploiting that feature to fight tumor cells. This specialized type of oncology is called cancer immunotherapy (or sometimes immuno-oncology) and it is…
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Finding Faces in DNA Traces
In 2017, seven years after a woman was sexually assaulted in broad daylight police in South Florida turned to the forensic DNA phenotyping company Parabon NanoLabs in a last resort attempt to identify a suspect. Within a few weeks, the Virginia-based company provided Davie…
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Precision medicine for the masses: CAR-T as a real-time use case
High expectations, mounting interest by pharma and biotech investors, growing focus on value, and occasionally breathless news reporting. These are some of the artefacts that surround fast-moving developments in the fields of precision medicine, immunotherapy, and cell and gene…
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The Myth Slayers
By now, most of us have read the stories about the upheaval DNA testing can cause by exposing unwanted pregnancies, extramarital affairs and secret adoptions. What is often less appreciated is how it is upending scholars’ understanding of human history and evolution, including…
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“Woke science” in the genomics era
Dr Keolu Fox stresses that we must see Indigenous groups as research partners, not guinea pigs. Scientists do not have the best reputation for being sensitive to different cultures and recognising injustice; in the ever-moving era of genomics, how will scientific research remain…
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The healing power of poop
Dog owners have all experienced them. Those cringe-worthy moments when the beloved family pet lick’s another dog’s anus, or tries to eat its poop. As odd as it seems, however, such behavior is hardly restricted to dogs and other canids. Many animals regularly eat one another’s…
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All you need to know about the 1000 Genomes Project
How different are we genetically? No two humans are identical with respect to their DNA sequences. The complete stretch of DNA is present within 23 chromosome pairs in individuals: one set inherited from the mother and the other from the father. As of 2018, a total of 660…