The Cancer Letter
The leading source for information on the issues that shape oncology since 1973
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Latest posts
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Cercek: “The majority of patients in AZUR-1 in a global study were able to avoid all of standard of care”
On Oct. 19, FDA granted an accelerated approval to dostarlimab-gxly (Jemperli) for the treatment of patients with previously untreated stage 2 or stage 3 rectal cancer that is mismatch repair deficient or microsatellite instability–high, as determined by an FDA-authorized test.…
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NCI’s new CCSG is the result of “thousands of hours” of listening, negotiations, surprises
Late next month, NCI is expected to publish the new criteria it uses to bestow designations on America’s network of cancer centers. This content is for Individual Subscription - Monthly ($55), Individual Subscription - Annual ($555), Introductory Subscription - non-renewing…
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NCAB ad hoc working group seeks to define its role as it approves eight reissue concepts
Members of the National Cancer Advisory Board’s ad hoc Working Group on Extramural Research Concepts and Programs at a recent meeting struggled to define the new group’s the role and raised concerns about some initial growing pains. This content is for Individual Subscription -…
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MSK’s Andrea Cercek: Oncology faces learning curve as dostarlimab challenges dMMR rectal cancer standard of care
Earlier this week, FDA granted an accelerated approval to dostarlimab-gxly (Jemperli), for adults with previously untreated stage 2 or stage 3 rectal cancer that is mismatch repair deficient or microsatellite instability-high, marking a celebratory moment for the field. This…
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Facing stage 4 cholangiocarcinoma, Keaton Herzer moved mountains to take off-label therapy, get a transplant
Keaton Herzer had never even heard of cholangiocarcinoma when he was diagnosed in 2025. He was 34 years old, living in Colorado with his wife—his high school sweetheart—and their brand-new baby boy. His symptoms were barely noticeable: a few days of abdominal pain on his right…
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Lifesaving vaccines: Using KRAS to harness the power of the immune system
Neeha Zaidi, MD, is turning the tables on pancreatic cancer. Mutations to a gene called KRAS—a cancer driver common to almost all pancreatic cancers—are now a target for prevention and treatment. Dr. Zaidi, an immunotherapy and pancreatic cancer expert, is studying KRAS…
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HHS announces initiative to improve breast cancer screening and early detection
HHS, through the recently announced Office of Women’s Health, announced taht it will be pursuing a collaboration with the Agency for Healthcare Research and Quality and DenseBreast-info.org to strengthen breast cancer screening, expand breast density education, and improve…
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CDC Deputy Director Jennifer Shuford resigns
Jennifer Shuford, deputy director of the Centers for Disease Control and Prevention appointed by President Trump to steady the agency, has resigned. This content is for Individual Subscription - Monthly ($55), Individual Subscription - Annual ($555), Introductory Subscription -…
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Cost of family insurance plans rose for workers in 2026, KFF survey finds
Premiums for family health insurance plans sponsored by employers have risen 9% from 2025 to 2026, according to the Kaiser Family Foundation’s annual survey of large and small employers. This content is for Individual Subscription - Monthly ($55), Individual Subscription -…
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Wells Messersmith named director of CU Anschutz Cancer Center
Wells Messersmith was named director of the University of Colorado Anschutz Cancer Center, effective Oct. 1. This content is for Individual Subscription - Monthly ($55), Individual Subscription - Annual ($555), Introductory Subscription - non-renewing ($60), Group 1 - Individual…
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Ned Sharpless named president-elect of the AACR Academy
Norman E. Sharpless has been named 2026-2027 president-elect of the American Association for Cancer Research Academy by the fellows of the AACR Academy. This content is for Individual Subscription - Monthly ($55), Individual Subscription - Annual ($555), Introductory…